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Which treatment is NOT used for cyanide poisoning?

  1. Sodium nitrite

  2. Amyl nitrite

  3. Sodium thiosulfate

  4. Calcium gluconate

The correct answer is: Calcium gluconate

In the context of cyanide poisoning, it’s essential to understand the role of specific antidotes used in treatment. Sodium nitrite and amyl nitrite work by converting hemoglobin to methemoglobin, which binds to cyanide, allowing it to be excreted. Sodium thiosulfate acts as a sulfur donor, facilitating the conversion of cyanide to thiocyanate, which is less toxic and easily eliminated by the kidneys. Calcium gluconate, on the other hand, does not play a role in the treatment of cyanide toxicity. It is primarily used to treat calcium deficiency and conditions such as hypocalcemia or hyperkalemia. Therefore, while it is an important medication in other emergency contexts, it is not utilized as an antidote for cyanide poisoning. Understanding the specific applications of these treatments emphasizes the importance of targeted interventions in managing poisoning cases effectively.