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What does Rouleaux formation indicate?

  1. Low blood pressure

  2. Aggregation of red blood cells

  3. Infection in the bloodstream

  4. High platelet count

The correct answer is: Aggregation of red blood cells

Rouleaux formation refers to the stacking or clumping of red blood cells, which can be observed under a microscope. This phenomenon occurs when red blood cells begin to aggregate due to changes in blood plasma protein levels, specifically an increase in certain proteins like fibrinogen or immunoglobulins. The presence of Rouleaux formation can be indicative of various conditions, such as inflammation, multiple myeloma, or other disorders that increase plasma proteins. It is an important diagnostic feature, as it helps healthcare providers understand the underlying pathological processes occurring in the body. Understanding the significance of Rouleaux formation is crucial in clinical settings for assessing and diagnosing potential health issues related to the blood and overall health status.