NREMT Paramedic Practice

Isoproterenol is known to be deactivated by which type of solution?

1. Acidic solutions

2. Neutral solutions

3. Alkaline solutions

4. Hypertonic solutions

The correct answer is: Alkaline solutions

Isoproterenol, a synthetic catecholamine used primarily for its bronchodilator and cardiac stimulant effects, is known to be deactivated in alkaline solutions. The chemical structure of isoproterenol can undergo degradation through a process called oxidation, which is accelerated in alkaline environments. The high pH associated with alkaline solutions can promote the breakdown of the medication, leading to a loss of potency and efficacy. This insight is crucial for healthcare providers, as it underscores the importance of proper storage and preparation of isoproterenol in clinical settings. For instance, when handling medications that are sensitive to pH, understanding the compatibility with solutions will ensure that the drug remains effective for patient care. Conversely, acidic and neutral solutions generally do not lead to the same level of degradation, making them safer alternatives for maintaining the stability of isoproterenol. Hypertonic solutions, while relevant in other contexts, do not specifically cause deactivation of isoproterenol.