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In what scenario would a Beta 2 blocker be contraindicated?

  1. Asthma attack

  2. Congestive heart failure

  3. Hypertension

  4. Bronchoconstriction

The correct answer is: Bronchoconstriction

A Beta 2 blocker would be contraindicated in a scenario involving bronchoconstriction because these medications block the action of epinephrine and norepinephrine at beta receptors, which can lead to worsening bronchial constriction. In patients with respiratory conditions such as asthma or chronic obstructive pulmonary disease, maintaining bronchodilation is critical. Beta 2 receptors are primarily located in the smooth muscle of the airways, and their activation promotes bronchodilation. Blocking these receptors may exacerbate respiratory distress or cause significant complications due to narrowing of the airways. In contrast, while other situations like asthma attacks are concerning when considering a Beta 2 blocker, the specific threat of acute bronchoconstriction makes it imperative to avoid the use of these blockers in that setting. This highlights the importance of understanding the pharmacological effects of medications and the specific receptors they target in managing respiratory conditions effectively.